A música Give Me Novacaine da banda Green Day fala sobre a busca por um alívio da dor e ansiedade mental, uma metáfora para a anestesia emocional em tempos difíceis. Parte do álbum American Idiot de 2004, reflete críticas sociais e pessoais.
Take away the sensation inside Bittersweet migraine in my head It's like a throbbing toothache of the mind I can't take this feeling any more
Drain the pressure from the swelling This sensation's overwhelming Give me a long kiss goodnight and everything will be alright Tell me that I won't feel a thing So give me novacaine
Out of body and out of mind Kiss the demons out of my dreams I get the funny feeling that's alright Jimmy says it's better than air N.C.
Drain the pressure from the swelling This sensation's overwhelming Give me a long kiss goodnight and everything will be alright Tell me that I won't feel a thing So give me novacaine Oh novacaine
Drain the pressure from the swelling This sensation's overwhelming Give me a long kiss goodnight and everything will be alright Tell me Jimmy I won't feel a thing So give me novacaine